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- Pediatric granular cell tumor in the posterior wall of the larynx extending to the trachea
- Jungsuk Ahn, Na Rae Kim, Yong Han Sun
- J Pathol Transl Med. 2020;54(4):336-339. Published online April 15, 2020
- DOI: https://doi.org/10.4132/jptm.2020.02.28
- 3,232 View
- 115 Download
- 1 Web of Science
- 1 Crossref
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Abstract
PDF - Granular cell tumor (GCT) is a slow-growing benign neoplasm that can be found in any organ. Pediatric laryngotracheal GCT is rare. We experienced a 6-year-old boy suffering from a barking cough and symptoms of stridor and croup for one month. Head and neck computed tomography revealed a protruding mass that occluded 60% of the airway lumen. Under the impression of hemangioma or papilloma, excision revealed a submucosal non-encapsulated mass. Histologically, the mass was composed of sheets of large polyhedralshaped tumor cells containing plump eosinophilic granular cytoplasm and centrally placed, small, bland-appearing nuclei. The tumor cells were positive for S-100 protein, and voluminous eosinophilic cytoplasm was stained by diastase-resistant periodic acid-Schiff. The present report describes a unique case of a huge pediatric laryngeal GCT extending to the subglottic trachea. We also review the clinical course of pediatric laryngotracheal GCT and emphasize the importance of diagnosing GCT in children.
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Citations
Citations to this article as recorded by
- Pediatric granular cell tumor of the larynx: A case report and literature review
Jing Ke, Junwei Xiong, Juhong Zhang, Haiyu Ma, Wei Yuan
Journal of Cancer Research and Therapeutics.2023; 19(4): 1070. CrossRef
- Pediatric granular cell tumor of the larynx: A case report and literature review
Brief Case Report
- A Case of Primary Subpleural Pulmonary Microcystic Myxoma Coincidentally Occurred with Pulmonary Adenocarcinoma
- Jungsuk Ahn, Na Rae Kim, Seung Yeon Ha, Keun-Woo Kim, Kook Yang Park, Yon Mi Sung
- J Pathol Transl Med. 2015;49(3):274-278. Published online May 15, 2015
- DOI: https://doi.org/10.4132/jptm.2015.03.12
- 6,972 View
- 50 Download
- 2 Web of Science
- 1 Crossref
Original Article
- Cytologic Features of
ALK -Positive Pulmonary Adenocarcinoma - Seung Yeon Ha, Jungsuk Ahn, Mee Sook Roh, Joungho Han, Jae Jun Lee, Boin Lee, Jun Yim
- Korean J Pathol. 2013;47(3):252-257. Published online June 25, 2013
- DOI: https://doi.org/10.4132/KoreanJPathol.2013.47.3.252
- 6,864 View
- 29 Download
- 9 Crossref
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Abstract
PDF
Background The aim of this study was to determine the cytologic features of anaplastic lymphoma kinase (
ALK ) expressing pulmonary adenocarcinoma.Methods We analyzed the cytopathological findings of 15 cases of endobronchial ultrasound guided aspiration and a case of bronchial washing. These cases were selected based on the histomorphology of
ALK -rearranged lung adenocarcinoma.Results Cytology showed mucinous (81.3%) and hemorrhagic (50%) backgrounds. The cells were arranged in tubulopapillary or tubulocribriform patterns (93.8%), and clusters (56.3%) admixed with signet ring cell features (87.5%). The tumor cells were monotonous and uniform with vesicular nuclei and a small nucleolus.
Conclusions The characteristic findings were sheets showing a tubulopapillary or tubulocribriform appearance, with vesicular nuclei and a bland chromatin pattern (p<0.001). Scattered signet ring cells were helpful in suggesting
ALK -positive adenocarcinoma (p<0.001).-
Citations
Citations to this article as recorded by- Machine learning‐based gene alteration prediction model for primary lung cancer using cytologic images
Shuhei Ishii, Manabu Takamatsu, Hironori Ninomiya, Kentaro Inamura, Takeshi Horai, Akira Iyoda, Naoko Honma, Rira Hoshi, Yuko Sugiyama, Noriko Yanagitani, Mingyon Mun, Hitoshi Abe, Tetuo Mikami, Kengo Takeuchi
Cancer Cytopathology.2022; 130(10): 812. CrossRef - Fine‐needle aspiration cytology of non‐small cell lung carcinoma: A paradigm shift
Pranab Dey, Ratan Kumar Ghosh
Diagnostic Cytopathology.2019; 47(4): 351. CrossRef - Qualitative and quantitative cytomorphological features of primary anaplastic lymphoma kinase‐positive lung cancer
Ryuko Tsukamoto, Hiroyuki Ohsaki, Sho Hosokawa, Yasunori Tokuhara, Shingo Kamoshida, Toshiko Sakuma, Tomoo Itoh, Chiho Ohbayashi
Cytopathology.2019; 30(3): 295. CrossRef - Primary signet-ring adenocarcinoma of the lung: A rare lung tumor
Varun Rajpal, Rahul Kumar Sharma, Charul Dabral, Deepak Talwar
South Asian Journal of Cancer.2019; 08(04): 257. CrossRef - Cytological features in eight patients with ALK‐rearranged lung cancer
Naoto Kuroda, Masahiko Ohara, Yukari Wada, Kaori Yasuoka, Keiko Mizuno, Kenji Yorita, Chiho Obayashi, Kengo Takeuchi
Diagnostic Cytopathology.2018; 46(6): 516. CrossRef - Cytological markers for predicting ALK‐positive pulmonary adenocarcinoma
K. Miyata, S. Morita, H. Dejima, N. Seki, N. Matsutani, M. Mieno, F. Kondo, Y. Soejima, F. Tanaka, M. Sawabe
Diagnostic Cytopathology.2017; 45(11): 963. CrossRef - ALK-rearranged adenocarcinoma with extensive mucin production can mimic mucinous adenocarcinoma: clinicopathological analysis and comprehensive histological comparison with KRAS-mutated mucinous adenocarcinoma
Yoon Jin Cha, Joungho Han, Soo Hyun Hwang, Tae Bum Lee, Hojoong Kim, Jea Ill Zo
Pathology.2016; 48(4): 325. CrossRef - Cytomorphological identification of advanced pulmonary adenocarcinoma harboring KRAS mutation in lymph node fine‐needle aspiration specimens: Comparative investigation of adenocarcinoma with KRAS and EGFR mutations
Dae Hyun Song, Boram Lee, Yooju Shin, In Ho Choi, Sang Yun Ha, Jae Jun Lee, Min Eui Hong, Yoon‐La Choi, Joungho Han, Sang‐Won Um
Diagnostic Cytopathology.2015; 43(7): 539. CrossRef - Comprehensive analysis of RET and ROS1 rearrangement in lung adenocarcinoma
Seung Eun Lee, Boram Lee, Mineui Hong, Ji-Young Song, Kyungsoo Jung, Maruja E Lira, Mao Mao, Joungho Han, Jhingook Kim, Yoon-La Choi
Modern Pathology.2015; 28(4): 468. CrossRef
- Machine learning‐based gene alteration prediction model for primary lung cancer using cytologic images
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